Generation and characterization of human induced pluripotent stem cells (iPSCs) from three patients with age-related macular degeneration carrying rare variants in the CFH gene

Generation and characterization of human induced pluripotent stem cells (iPSCs) from three patients with age-related macular degeneration carrying rare variants in the CFH gene

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Age-related macular degeneration (AMD) is a major cause of vision loss among the elderly in the Western world.AMD is multifactorial eye disease with a strong genetic contribution.Here, we Exterior Door Handle Trims and Accessories report the generation and characterization of induced pluripotent stem cells Course a pied - Accessoires - Manchettes (iPSCs) derived from peripheral blood mononuclear cells of three patients with AMD carrying rare variants in the complement factor H (CFH) gene.These cell lines were generated for cellular studies investigating the disease mechanisms and developing therapeutic interventions for AMD.